From cryopreservation of tissue and the nutritional bioavailability of foods to computational modeling for biomedical imaging, experts in the Department of Mechanical Engineering are exploring ways to address human health issues.
Our experts investigate biomechanics at the molecular, cellular, and human body scales.
Their work includes exploring myosin protein for synthetic muscle, using DNA origami for nanomechanics of multiprotein systems, developing robotic interfaces for microsurgery, and making bio-inspired robots. They pair wearable medical devices with advanced analytics and machine learning to personalize rehabilitation for joint injuries and pathologies. They investigate the physiological mechanisms underlying sensory perception, feedback control of movement, and neuroplasticity in sensorimotor systems.
From implantable medical devices for neural probing and wireless temperature sensing to dissolvable transdermal drug delivery systems, our faculty and students develop and analyze manufacturing processes for bioinert, effective medical tools.
Examples include tissue engineering, a gluten sensing device, bio-micro fluidic device fabrication, 3D printed bones for surgical training, repairing and replacing damaged tissues and organs, and wearable devices for enhancing sensory, motor, and cognitive functions.
Researchers develop models and simulations with computational geometry, mesh generation, finite element method, and isogeometric analysis for applications like micro-scale computer simulations of the circulatory system and biomedical imaging. They use patient-specific geometry from musculoskeletal imaging and real-world movements captured by wearable sensors to design assistive devices and ergonomic products.
They are combining molecular dynamic simulations, machine learning, and statistical learning to understand and predict the properties and interactions of bio-molecules such as DNA and proteins.
Our experts develop sensors, surgical hardware, and physical modeling for the field of thermal energy in biology and medicine.
They apply their research to areas such as cryopreservation of tissue, cryosurgery, and heat and mass transfer in biological systems.
Faculty involved: Yoed Rabin
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Collaborators’ creation reveals how mechanical forces control genes
A LeDuc/Minden collaboration in mesofluidics—a medium-sized twist on microfluidics—was featured on the cover of the journal Lab on a Chip. The research team merged expertise in biomechanics, biology, and engineering to develop a new device.
Saving lives through advanced cryopreservation Opens in new window
Professor Yoed Rabin received a $1.6 million award from the National Heart, Lung, and Blood Institute of the National Institutes of Health to develop technology for cryopreservation, the preservation of tissues and organs at extremely low temperatures.
Center for the Mechanics and Engineering of Cellular Systems