This course explores methods for the design of electromechanical devices that physically interface with humans to improve biomechanical performance, such as robotic prostheses and exoskeletons. Students will learn about common physical disabilities and methods for generating and evaluating potential interventions. Students will learn about state-of-the-art actuation and sensing systems, and design selected types to meet dynamic performance criteria. We will cover technology for interfacing these devices with humans, and implications for the resulting biomechatronic systems. Students will learn experimental methods for evaluating intervention effectiveness, including inverse dynamics and metabolics analyses. Students will complete a final project that involves introduction of novel elements to a biomechatronic system. Students need a foundation in machine design and numerical tools such as Matlab, and will benefit from knowledge of dynamics and biomechanics.